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Association of Government Toxicologists |
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Upcoming AGT Seminar
Health Consequences/Management of Substance Use and Co-occurring Infections: Research at NIDA.
By
Jag
Khalsa, Ph.D
Division of Pharmacotherapies and Medical Consequences of Drug Abuse, National Institute on Drug Abuse, NIH, Bethesda, Maryland, USA.
7:00 pm, Thursday, March 25, 2010
(Preceded by AGT's traditional buffet available from 6:00 pm)
Small Dining Room
Uniformed Services University of the Health Sciences
Bethesda, MD
The Abstract:
Today substance use/abuse is a major problem in the world with about 200 million people 12 years or old who use an illicit drug, >19 million current substance users in the US alone. There are 40 million HIV-infected and about 200 million HCV-infected people in the world; about 1 million HIV-infected and 4 million HCV-infected people in the US. Although there are not many cases of TB among substance users in the US, almost one-third of the world’s population is infected with TB. Substance use alone costs the American society an estimated $530+ billion annually. Both substance use and co-occurring infections (HIV, HCV, TB, STDs, and others) are associated with serious adverse medical/health consequences affecting almost every physiological system. The National Institute on Drug Abuse (NIDA) supports about 85% of world’s research on substance use and infections. Currently we support basic, clinical, and translational research on substance use and infections in the domestic and international settings. For example, research programs include but not limited to the incidence and prevalence of HIV/AIDS, prevention and treatment of infections among IDUs, neuroAIDS, neuropsychiatric complications, cardiovascular, metabolic (including nutritional issues) and endocrine consequences of HIV/AIDS and drug abuse, drug-drug interactions among ARVs and medications used in the treatment of drug addiction and mental disorders. A strong emphasis is placed on the inclusion of minorities, underserved populations, women and children in research. This presentation will discuss various medical consequences of substance use and infections, management strategies, recent findings from published and on-going research at NIDA/NIH.
The Speaker:
Dr. Jag Khalsa is the Chief of the Medical Consequences Branch in the Division of Pharmacotherapies and Medical Consequences of Drug Abuse, the National Institute on Drug Abuse (NIDA), a part of the National Institutes of Health (NIH), DHHS. He received his Ph.D. in neuro-psycho-pharmacology from the University of Mississippi and postdoctoral training in CNS/Cardiovascular pharmacology at SK&F (now GlaxoSmith Kline), and Toxicology at the Stanford Research Institute. The Branch is responsible for developing and administering a national and international program of clinical research on Medical and Health Consequences of Drug Abuse and co-occurring infections (HIV, HCV, TB, STD, and others) including metabolic, endocrine and gastrointestinal disorders in drug addicts with or without HIV infection; pharmacokinetic/pharmacodynamic drug-drug interactions among drugs of abuse, and pharmacotherapeutic agents used in the treatment of infections (HIV, HCV) and drug addiction; and misuse of prescription drugs. Prior to joining NIDA in 1987, he served for about 10 years as a pharmacologist/toxicologist assessing safety including carcinogenic and teratogenic potential of chemicals [new drugs-INDs and NDAs] and food additives) and clinical evaluator (adverse consequences of drugs) at the US Food & Drug Administration. He has several publications in the field of pharmacology, toxicology, epidemiology and medicine. He has received several awards of meritorious/distinguished service from the FDA Commissioner, Director of Bureau of Foods, FDA, NIDA Director, NIH Director, Society on NeuroImmunePharmacology, the Life Time Achievement Awards from the U.S. Sikh Council on Religion and Education and the International Conference on Molecular Medicine, and commendation from the US Congressman E. Cummings. Incidentally, Dr. Khalsa also has degrees in Chemistry (B.Sc), pharmacy (B.Pharm), pharmacology/pharmacognosy [herbal pharmacology], M.Pharm), all from Gujarat University, India. He is married; has two sons and two grand daughters. Dr. Khalsa’s hobbies are: music and photography. He can be reached via E-mail: jk98p@nih.gov
To Register For This Meeting
To Register For This Meeting. Please register at the AGT website (http://www.agovtox.org/) by March 23, 2010. Indicate if you plan to partake in our gourmet buffet supper (complimentary to AGT members; $10 for non-member visitors). You are welcome to come early (5:00 - 6:30 pm) and observe the AGT Council meeting. Bring your colleagues to the talk and introduce them to the joys of AGT. For additional information contact Sabine Francke, 301-436-1308
*If you are not a member and wish to eat dinner with us, please bring $10.00 cash with you to the meeting and pay the AGT Treasurer, Jeff Yourick.
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Complete this form and submit it by March 23, 2010.
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Location and Security Measures in force on the NNMC Campus: If driving, you must enter the Naval Medical Center (NNMC) campus via Center Drive off of Wisconsin Avenue. When stopped by the guards, indicate that you are attending the AGT meeting at the Uniformed Services University of the Health Sciences (USUHS). Be prepared to present a photo ID. NNMC is right across the street from the NIH metro stop (Medical Center, Red Line). After clearing the security check, turn right at the next road (Palmer Road) and continue back to USUHS, which is the last large set of buildings on your left. At the end of Palmer, turn left to enter the underground parking garage. You may park in any garage parking spot not marked as "reserved." The small dinning room is one flight up, and may be reached by taking the outdoor stairs to the Courtyard, or by entering via the security office at the parking garage level.
Additional Security Note: The National Naval Medical Center observes security procedures appropriate to the threat environment. At a minimum, a valid, unexpired picture ID will be required. There may be times when two picture IDs will be required, as well as random interviews and vehicle searches. There may be times when your name must be registered with NNMC Security to get on the base, so register as early as you can for each AGT meeting. The base police also are on the lookout for driving violations. The speed limit on NNMC base is 20 miles per hour - and is strictly enforced. Be sure to come to a full stop and any pedestrian crossing with a stop sign. Pedestrians always have the right of way. You should always stop for pedestrians to cross the street, even at an unmarked crossing.
Directions:
Metro: Take the Red Line to the Medical Center stop. Once outside, turn around to cross Rockville Pike and enter the National Naval Medical Center campus. After showing ID to the guards, turn right to follow Palmer Avenue and walk approximately 10 minutes to the last large building on the left, which is the Uniformed Serivces University of the Health Sciences. Proceed left into the center of the USUHS complex and enter the building on the left to find the small dining room (beyond the main dining room).
Automobile from downtown Washington, DC: Take Wisconsin Avenue north to Bethesda. Make a right into the National Naval Medical Center, just after Jones Bridge Road. Turn right (Palmer Rd) and follow to USUHS. Turn left into USUHS parking garage at the end of Palmer. DO NOT PARK IN FRONT OF THE UNIVERSITY!
Automobile from I-495 Virginia: Take 495 towards Rockville. At the I-270/I-495 split, stay to the right on I-495. Take the exit for Rt. 355-Wisconsin Avenue-Bethesda. Turn left at the 3rd traffic signal - This is the entrance to National Naval Medical Center. Turn right (Palmer Rd) and follow to USUHS. Turn left into USUHS parking garage at the end of Palmer. DO NOT PARK IN FRONT OF THE UNIVERSITY!
Automobile from I-495 P.G. County/Baltimore: Take 495 towards Silver Spring. Exit at Connecticut Avenue-Chevy Chase. At the bottom of the exit, turn left onto Connecticut Avenue. Go to the second traffic light, which is Jones Bridge Road, and make a right. Turn right on Wisconsin Avenue, and take the first right into National Naval Medical Center. Turn (Palmer Rd) and follow to USUHS. Turn left into USUHS parking garage at the end of Palmer. DO NOT PARK IN FRONT OF THE UNIVERSITY!
Automobile from I-270: Take I-270 south. Stay to the left at the split, observe HOV restrictions during rush hour. Exit at Rt. 355-Wisconsin Avenue-Bethesda (left lane exit). Turn left at the 3rd traffic signal (South Wood Road- it is 2nd traffic light after Cedar lane) - This is the entrance to National Naval Medical Center. Turn right (Palmer Rd) (this is the first right after security check) and follow to USUHS. Turn left and go down into USUHS parking garage at the end of Palmer (4th Stop sign). DO NOT PARK IN FRONT OF THE UNIVERSITY!
