Those involved in the risk management of chemical substances are continually seeking new approaches, including those using computer-based technology, to make safety determinations more rapidly and also more accurately. The purpose of this meeting is to offer an updated look at the current level of maturity of the field of informatics and computational toxicology. Can the methods now available be trusted to provide reliable decision support information to aid risk evaluators not only to make faster and better decisions, but also to reduce the amount of animal testing necessary to provide information for judgements to be made?

On the first day, this meeting will begin with a symposium in which a general introduction to the field of informatics and computational toxicology will be presented. Those attending this session will hear about new computational techniques for data modeling and safety prediction, and how these tools are applied in the chemical and pharmaceutical industry, and by a regulatory agency. This session will end with a talk in which the future of this field will be discussed.

The afternoon of the first day will provide an opportunity for hands-on experience with six major informatics and computational safety predictive software systems in a vendor exhibition. This session will then be followed by parallel vendors' users' group meetings in which issues unique to each product are discussed. (Those that need to attend more than one of these meetings should bring a colleague to represent them!)

The second day of the meeting will be devoted exclusively to an intensive workshop at which the experience with different informatics and computational safety analysis software systems will be discussed in depth, with detailed emphasis on how these tools can be used successfully.

Please join us!

Any questions about the meeting content or arrangements may be addressed to Dan Benz.

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The organizers thank the Genetic Toxicology Association and the Association of Government Toxicologists for sponsoring and the National Capital Area Chapter of the Society of Toxicology for co-sponsoring this meeting. We especially thank the National Library of Medicine for allowing us to use their facilities.

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To register to attend this Meeting, send your name, affiliation, address, phone, FAX and e-mail to:

along with a check payable to the Genetic Toxicology Association in the amount of:

Early Registration Through May 28, 2003

After May 28, 2003 and On-site Registration

With your registration application, please also say that you obtained the information for this Meeting from the AGT or GTA Web site. We are sorry that we are not able to accept charge cards or purchase orders; please, checks only.

To apply for membership, go to: Association of Government Toxicologists or Genetic Toxicology Association.

Internet Special: Register for the Informatics and Computational Toxicology Meeting using the form below by May 28, 2003, and pay only the Early Registration fee upon arrival on the day of the meeting! {Note, to cover the sponsors' financial commitments, those who take advantage of this offer will be billed for one-half of their registration costs if they do not attend the meeting and no cancellation is made prior to 05/28/03. [To cancel, send an e-mail message to: gregory.erexson@covance.com no later than 05/28/03.]}

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The National Institutes of Health (NIH) are served by the Washington, DC METRO Red Line at Medical Center Station, Bethesda. Upon exiting to street level, turn left to go up the short stairway immediately in front of you. From the top of the stairs the National Library of Medicine’s multi-storied Lister Hill Building can be seen in the near distance ahead.

If coming by air, travel time to Bethesda is 45 - 60 minutes from National, Dulles or BWI Airports. For Washington Flyer Limo Service to Dulles or National, call (888) WASHFLY at least two hours in advance of your desired pick up time. The METRO Blue and Yellow lines also serve National Airport. For BWI airport, call the BWI Supershuttle at (800) BLUEVAN, or take the free bus to the BWI train station, and a MARC or Amtrak train to DC Union Station.

If coming by train, leave DC Union Station via the METRO Red Line toward Shady Grove. Travel time to Medical Center Station is approximately 30 minutes.

Attendees of this meeting are strongly urged to use public transportation. However, if you must drive to the meeting, note that parking is strictly limited to spaces clearly marked for visitors, and is usually restricted to two or three hours. Also please note the new NIH visitor security procedures.

Major roads in and around Bethesda, Maryland

NIH visitor information

NIH security information

Map of NIH showing (extremely limited) parking

Map of the National Library of Medicine environs, including parking

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The following two hotels are in Bethesda, Maryland and are within reasonable walking distance of the National Library of Medicine (at 8600 Wisconsin Avenue).

The following two hotels are also in Bethesda, Maryland but significantly farther away from NLM.

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